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2.
Arq. bras. neurocir ; 40(3): 257-262, 15/09/2021.
Article in English | LILACS | ID: biblio-1362151

ABSTRACT

Pediatricmeningiomas are rare and account for only 2.2% of the central nervous system (CNS) tumors. In this age group, they aremore frequently located in atypical sites, such as, mainly, the ventricular system, with a frequency of 8.8 to 13.6%. Adding this to the fact that the angiomatous subtype constitutes only 2.1% of allmeningiomas, the rarity of the case reported here is corroborated. We report a 17-year-old female patient diagnosed with intraventricular angiomatous meningioma; she underwent surgical resection of the tumor in the body and frontal horn of the right lateral ventricle, and there were no neurological sequelae. With a follow-up of 26 months, there was no recurrence and the patient had clinical stability. Intraventricular tumors usually have slow growth and reach a considerable size until they cause symptoms and then are diagnosed. In addition, the deep location of the tumor and its proximity to eloquent areas make these tumors a neurosurgical challenge. The angiomatous subtype, due to the presence of hypervascularization (consisting of > 50% of vascular components), may, in some cases, hinder surgical resection as well as be erroneously diagnosed. However, surgical treatment aimed at total resection of the lesion remains the conduct of choice in the case reported here, especially in patients in the first two decades of life, in which the use of radiation is avoided. Specifically when it comes to the surgery, we chose a transcalosal approach that allows a good transoperative visualization of the lesion when located in the body and frontal horn of the lateral ventricle.


Subject(s)
Humans , Female , Adolescent , Lateral Ventricles/surgery , Meningeal Neoplasms/surgery , Meningioma/surgery , Treatment Outcome , Meningeal Neoplasms/diagnostic imaging , Meningioma/pathology , Meningioma/diagnostic imaging
3.
Arq. bras. neurocir ; 40(3): 277-279, 15/09/2021.
Article in English | LILACS | ID: biblio-1362157

ABSTRACT

Sarcoidosis is a systemic disease characterized by granulomatous inflammation. Pulmonary and lymphatic granulomatous involvement are common.We present a rare case report of involvement of the central nervous system affecting the ocular region and mimicking optic nerve sheath meningioma. We report the case of a 79-year-old female patient with progressive visual impairment with an evolution of 4 years. Amagnetic resonance imaging scan of the cranium with gadolinium and intense homogeneous contrast enhancement revealed an expansive lesion in the right optic nerve, at the height of the optic canal. The patient was submitted to the neurosurgical approach with lesion biopsy, which showed sarcoidosis of the central nervous system. Due to the rarity of central nervous system involvement, the diagnosis of this pathologymay unfortunately be postponed. The present article aims to elucidate this pathology as a differential diagnosis of retro-orbital tumors.


Subject(s)
Humans , Female , Aged , Sarcoidosis/diagnosis , Optic Nerve Neoplasms/surgery , Meningeal Neoplasms/surgery , Meningioma/surgery , Cranial Fossa, Anterior/surgery , Diagnosis, Differential , Meningeal Neoplasms/diagnostic imaging , Meningioma/pathology , Meningioma/diagnostic imaging
4.
Rev. medica electron ; 43(3): 844-854, 2021. tab, graf
Article in Spanish | LILACS, CUMED | ID: biblio-1289822

ABSTRACT

RESUMEN En muchas ocasiones, los pacientes con tumores cerebrales tienen una variedad de síntomas psiquiátricos inespecíficos. Algunos de estos pueden constituir la primera o única manifestación del tumor, sin la presencia de ningún síntoma o signo neurológico. El diagnóstico ha de basarse en la anamnesis completa y en la exploración neurológica; la neuroimagen confirmará el diagnóstico clínico. Con el presente trabajo se describió la asociación inusual de hematoma subdural crónico y meningioma parasagital en un caso presentado. Se trató de un paciente de 68 años con antecedentes de esquizofrenia. Acudió a consulta con una hemiparesia izquierda. Se le realizó una tomografía axial computarizada de cráneo y arrojó un hematoma subdural crónico y un meningioma parasagital derecho. Se le aplicó tratamiento quirúrgico en dos tiempos operatorios. Su evolución posquirúrgica transcurrió sin complicaciones (AU).


ABSTRACT In many cases, patients with brain tumors have a variety of nonspecific psychiatric symptoms. Some of them can be the first or the only manifestation of the tumor, without presenting any neurological signs or symptoms. The diagnosis must be based on the complete anamnesis and on the neurological examination. The neuroimaging will confirm the clinical diagnosis. The unusual association of a chronic subdural hematoma and a parasagittal meningioma was described in a case presented in the current work. It dealt with a patient, aged 68 years with antecedents of schizophrenia. He assisted the consultation with left hemiparesis. A skull computed tomography showed a chronic subdural hematoma and a right parasagittal meningioma. He underwent a two-steps surgery. His post-surgery evolution ran without complications (AU).


Subject(s)
Humans , Male , Hematoma, Subdural, Chronic/diagnosis , Meningioma/diagnosis , Paresis/diagnosis , Schizophrenia/pathology , Hematoma, Subdural, Chronic/surgery , Hematoma, Subdural, Chronic/therapy , Hematoma, Subdural, Chronic/epidemiology , Meningioma/surgery , Meningioma/therapy , Meningioma/epidemiology , Neoplasms/diagnosis
5.
Arq. bras. neurocir ; 40(2): 174-178, 15/06/2021.
Article in English | LILACS | ID: biblio-1362230

ABSTRACT

Anaplastic or malignant meningiomas that are classified as World Health Organization (WHO) grade III account for less than 1% of all meningiomas diagnosed. Despite the aggressive course, distant metastases are a rarity, occurring in only 0.1% to 0.2% of cases. We report the case of a 56-year-old woman who presented with parasagittal benign meningioma that underwent malignant transformation along with metastasis into the right orbitosphenoid region. The clinical, radiological, and histopathological aspects are highlighted, with an emphasis on the natural history of meningiomas.


Subject(s)
Humans , Female , Middle Aged , Superior Sagittal Sinus/surgery , Meningeal Neoplasms/surgery , Meningioma/pathology , Neoplasm Metastasis , Superior Sagittal Sinus/pathology , Meningeal Neoplasms/pathology , Meningioma/surgery , Meningioma/diagnostic imaging
6.
Arq. bras. neurocir ; 39(2): 149-153, 15/06/2020.
Article in English | LILACS | ID: biblio-1362530

ABSTRACT

Introduction Meningiomas are the most common primary intracranial tumors, accounting for up to 35% of the neoplasms in this category. Approximately 10­20% of these neoplasms are histologically atypical, and the lymphoplasmacyte-rich meningioma (LPM) corresponds to a very rare subtype of meningioma that is characterized histopathologically by massive infiltrates of inflammatory cells. The case described in the present study is the sixth case of an intraventricular LPM found in the literature and the first case considering the location in the third ventricle. Case Description A 21-year-old male without previous comorbidities sought medical attention due to visual impairment (complaining of intermittent visual blur) for 2 months. A magnetic resonance imaging of the brain confirmed the presence of a well-delimited solid mass in the third ventricle of 3.0 2.3 cmwith a cystic component that extended itself inferiorly and distorted the visual pathway anatomy. Neurosurgeons decided to access the lesion using an interhemispheric transcallosal approach with a transforaminal access, and the lesion was resected completely. The patient has an ambulatorial endocrinological follow-up and is neurologically stable 6 months after the procedure. No new visual deficits were noted. Conclusion Lymphoplasmacyte-rich meningioma is a very rare intracranial tumor, and the involvement of the third ventricle make this case unique.


Subject(s)
Humans , Male , Adult , Third Ventricle/surgery , Third Ventricle/pathology , Meningeal Neoplasms/surgery , Meningioma/surgery , Meningeal Neoplasms/pathology , Meningeal Neoplasms/diagnostic imaging , Meningioma/pathology , Meningioma/diagnostic imaging
7.
Arq. bras. neurocir ; 39(2): 61-67, 15/06/2020.
Article in English | LILACS | ID: biblio-1362492

ABSTRACT

Objective To describe our surgical techniques, analyze their safety and their postoperative outcomes for foramen magnum tumors (FMTs). Methods From 1986 to 2014, 34 patients with FMTs underwent surgeries using either the lateral suboccipital approach, standard midline suboccipital craniotomy, or the far lateral approach, depending on the anatomic location of the lesions. Results In the present series, there were 22 (64.7%) female and 12 (35.2%)male patients. The age of the patients ranged from12 to 63 years old.We observed 1 operativemortality (2.9%). A total of 28 patients (82.3%) achieved a score of 4 or 5 in the Glasgow Outcome Scale (GOS). Gross total resection (GTR) was obtained in 22 (64.7%) patients. After the surgery, 9 (26%) patients developed lower cranial nerve dysfunction (LCNd) weakness. The follow-up varied from 1 to 24 years (mean: 13.2 years). Conclusion Themajority of tumors located in the FMcan be safely and efficiently removed usingeither thelateral suboccipital approach, standardmiddlelinesuboccipital craniotomy, or the far lateral approach, depending on the anatomic location of the lesions.


Subject(s)
Neurosurgical Procedures/methods , Foramen Magnum/surgery , Meningeal Neoplasms/surgery , Meningioma/surgery , Medical Records , Retrospective Studies , Treatment Outcome , Craniotomy/methods , Foramen Magnum/abnormalities , Foramen Magnum/physiopathology , Meningioma/pathology
8.
Arq. bras. neurocir ; 39(1): 5-11, 15/03/2020.
Article in English | LILACS | ID: biblio-1362403

ABSTRACT

Meningiomas are among the most common central nervous system tumors, with an incidence that ranges from 15% to 40% of intracranial tumors. Of these, only 0.5% to 3% are intraventricular, and the rarest of them occurs in the fourth ventricle. Fourth-ventricle meningiomas originate generally fromthe choroid plexus and have no dural adhesions. Most often, they manifest in young patients, around 41 years of age, with a possible predominance in females, through intracranial hypertension and cerebellar syndromes. The treatment consists of surgical resection, which commonly presents good results due to the characteristics of the tumor. So, for better preoperative planning, the radiological differentiation of the most frequent tumors in this location is important. Themost common histologic subtypes are fibroblastic and meningothelial, both grade I according to the World Health Organization (WHO), although there are reports of tumors of grades II and III. We report a case ofmeningioma of the fourth ventricle operated in our institution, and we have conducted a literature review, through which we found that 57 cases have been reported so far, with the first one reported in 1938.


Subject(s)
Humans , Male , Adult , Fourth Ventricle/pathology , Meningioma/surgery , Meningioma/epidemiology , Meningioma/diagnostic imaging , Cerebellar Neoplasms/epidemiology , Meningioma/physiopathology
9.
Arq. bras. neurocir ; 39(1): 12-15, 15/03/2020.
Article in English | LILACS | ID: biblio-1362407

ABSTRACT

Chordoid meningiomas (CMs) are a rare subgroup of tumors, accounting for 0.5% of all meningiomas. Chordoid meningioma tumors correspond to World Health Organization (WHO) Grade II lesions and behave aggressively, with an increased likelihood of recurrence. There are few genetic studies about CMs, but we understand that there is deletion at many chromosomal loci. Histologically, CMs are characterized by strands and cords of meningothelial cells arranged in a mucinous stroma. Morphologically, it can mimic other chondroid and myxoid tumors within the brain and its vicinity, thus posing a diagnostic challenge. Chordoid meningiomas have an aggressive clinical course and a propensity to recur compared with classical meningiomas. The goal of the treatment is surgery, with total resection of the tumor; however, due to its high degree of recurrence, radiotherapy is often necessary as an adjuvant treatment.


Subject(s)
Humans , Female , Adult , Meningeal Neoplasms/pathology , Meningioma/surgery , Meningioma/physiopathology , Meningioma/diagnostic imaging , Recurrence , Meningioma/epidemiology
10.
Rev. medica electron ; 41(6): 1367-1381, oct.-dic. 2019. tab, graf
Article in Spanish | LILACS, CUMED | ID: biblio-1094136

ABSTRACT

RESUMEN Introducción: los meningiomas constituyen la segunda causa de tumores cerebrales primarios, en el adulto. Representan hasta el 32 % del total de los mismos. Objetivo: describir el comportamiento del meningioma intracraneal en los pacientes investigados. Materiales y métodos: se realizó un estudio analítico, descriptivo, retrospectivo a los pacientes neurointervenidos con meningioma intracraneal, en el Servicio de Neurocirugía del Hospital Docente Universitario "Comandante Faustino Pérez Hernández", de la provincia Matanzas. En el período comprendido entre el 1ero de enero de 2017 al 1ero de enero del 2019. Los 15 pacientes intervenidos conformaron el universo de estudio. Resultados: la media poblacional fue de 55 años. Predominó el sexo femenino en un 73,3 %. La cefalea fue la manifestación clínica más frecuente, igualmente, que los meningiomas de la convexidad cerebral. En cuanto a la topografía, la media del tamaño de la lesión fue de 4,4 cm. La variedad meningotelial (40 %) fue la que predominó. El grado II de resección fue el que más se empleó. El edema cerebral postquirúrgico predominó en un 26,6 %. La puntuación de la escala de Karnofsky al egreso fue superior que al ingreso. Conclusiones: cuanto más precoz se realice el diagnóstico clínico y tratamiento quirúrgico en los pacientes portadores de meningioma, mejor será su calidad de vida al egreso (AU).


ABSTRACT Introduction: meningiomas are the second cause of primary brain tumors in adults, representing up to 32 % of the total. Objective: to describe the behavior of intracranial meningioma in the studied patients. Materials and methods: a retrospective, descriptive, analytical study was conducted on neurosurgery patients with intracranial meningioma in the Neurosurgery service of the University Teaching Hospital "Comandante Faustino Pérez Hernández" of the province of Matanzas, in the period from January 1st 2017 to January 1st, 2019. The 15 patients undergoing neurosurgery were the study universe. Results: the population mean was 55 years; female sex prevailed (73.3 %). Headache was the most frequent clinical manifestation as well as meningiomas of cerebral convexity in terms of topography. The average lesion size was 4.4 cm; the meningothelial variety (40 %) was the most commonly found; grade II resection was the most used one. Post-surgical cerebral edema (26.6%) predominated. Karnofsky scale score at discharge was higher than at admission. Conclusions: the earlier the clinical diagnosis and surgical treatment are performed in patients with meningioma the better will be their quality of life at discharge (AU).


Subject(s)
Humans , Adult , Middle Aged , Aged , Brain Neoplasms/epidemiology , Meningioma/epidemiology , Quality of Life , Laboratory and Fieldwork Analytical Methods , Epidemiology, Descriptive , Retrospective Studies , Meningioma/surgery , Meningioma/complications , Meningioma/diagnosis , Neurosurgery
11.
Braz. j. otorhinolaryngol. (Impr.) ; 85(4): 427-434, July-Aug. 2019. graf
Article in English | LILACS | ID: biblio-1019590

ABSTRACT

Abstract Introduction: One of the main concerns in endoscopic endonasal approaches to the skull base has been the high incidence and morbidity associated with cerebrospinal fluid leaks. The introduction and routine use of vascularized flaps allowed a marked decrease in this complication followed by a great expansion in the indications and techniques used in endoscopic endonasal approaches, extending to defects from huge tumours and previously inaccessible areas of the skull base. Objective: Describe the technique of performing endoscopic double flap multi-layered reconstruction of the anterior skull base without craniotomy. Methods: Step by step description of the endoscopic double flap technique (nasoseptal and pericranial vascularized flaps and fascia lata free graft) as used and illustrated in two patients with an olfactory groove meningioma who underwent an endoscopic approach. Results: Both patients achieved a gross total resection: subsequent reconstruction of the anterior skull base was performed with the nasoseptal and pericranial flaps onlay and a fascia lata free graft inlay. Both patients showed an excellent recovery, no signs of cerebrospinal fluid leak, meningitis, flap necrosis, chronic meningeal or sinonasal inflammation or cerebral herniation having developed. Conclusion: This endoscopic double flap technique we have described is a viable, versatile and safe option for anterior skull base reconstructions, decreasing the incidence of complications in endoscopic endonasal approaches.


Resumo Introdução: Uma das principais preocupações em abordagens endoscópicas endonasais da base do crânio tem sido a alta incidência e morbidade associada a fístulas liquóricas. A introdução e o uso rotineiro de retalhos vascularizados permitiram uma acentuada redução dessa complicação, seguida por uma grande expansão nas indicações e técnicas utilizadas nas abordagens endoscópicas endonasais, incluindo grandes tumores e áreas anteriormente inacessíveis da base do crânio. Objetivo: Descrever a técnica cirúrgica realizando uma reconstrução endoscópica multicamadas da base anterior do crânio com duplo retalho, sem craniotomia. Método: Descrição passo a passo da técnica endoscópica com duplo retalho (retalhos vascularizados nasoseptal e pericraniano e enxerto livre de fascia lata), utilizados e ilustrados em dois pacientes com meningioma do sulco olfatório submetidos à cirurgia por via endoscópica endonasal. Resultados: Em ambos os pacientes procedeu-se ressecção total macroscópica seguido de reconstrução da base anterior do crânio com os retalhos nasoseptal e pericraniano onlay e enxerto livre de fáscia lata inlay. Os pacientes apresentaram uma excelente recuperação, sem sinais de fístula liquórica, meningite, necrose do retalho, inflamação meníngea crônica ou sinonasal ou hérnia cerebral. Conclusão: A técnica endoscópica de duplo retalho, como descrita, trata-se de uma opção viável, versátil e segura para as reconstruções da base anterior do crânio, diminuindo a incidência de complicações em abordagens cirúrgicas endoscópicas endonasais.


Subject(s)
Humans , Male , Female , Adult , Middle Aged , Skull Base Neoplasms/surgery , Plastic Surgery Procedures/methods , Endoscopy/methods , Nasal Cavity/surgery , Postoperative Complications , Surgical Flaps , Cadaver , Magnetic Resonance Imaging , Tomography, X-Ray Computed , Cerebrospinal Fluid Rhinorrhea/surgery , Minimally Invasive Surgical Procedures/methods , Meningeal Neoplasms/surgery , Meningeal Neoplasms/diagnostic imaging , Meningioma/surgery , Meningioma/diagnostic imaging
12.
Rev. medica electron ; 41(2): 537-545, mar.-abr. 2019. graf
Article in Spanish | LILACS, CUMED | ID: biblio-1004286

ABSTRACT

RESUMEN Se presentó un caso de una paciente de 70 años de edad, con antecedentes patológicos personales de hipertensión arterial controlada, además de un síndrome demencial instaurado hace 5 años aproximadamente. Con un diagnóstico presuntivo de una demencia tipo Alzheimer y sin estudios desde el punto de vista imagenológico. Se le realizaron diversos estudios que arrojaron una lesión extraaxial interpretada como un meningioma del tercio medio del ala del esfenoides. Se le aplicó una resección tumoral de la totalidad de la lesión, su evolución postquirúrgica fue satisfactoria.


ABSTRACT The case presented is the one of a female patient aged 70 years, with personal pathological antecedents of controlled arterial hypertension besides dementia syndrome for around five years, presumptively diagnosed as Alzheimer-kind dementia without imaging studies. She underwent several studies showing an extra axial lesion that was interpreted as meningioma of the medial third of the sphenoid wing. The tumor resection of the entire lesion was carried out; the post-surgery evaluation was satisfactory.


Subject(s)
Humans , Female , Aged , Sphenoid Bone , Skull Base Neoplasms , Meningioma/surgery , Meningioma/diagnosis , Meningioma/diagnostic imaging , Alzheimer Disease/diagnosis , Hypertension/drug therapy
14.
Arq. bras. neurocir ; 37(4): 362-366, 15/12/2018.
Article in English | LILACS | ID: biblio-1362630

ABSTRACT

Foramen magnum (FM) tumors represent one of the most complex cases for the neurosurgeon, due to their location in a very anatomically complex region surrounded by the brainstem and the lower cranial nerves, by bony elements of the craniocervical junction, and by the vertebrobasilar vessels. Currently, the open approach of choice is a lateral extension of the posteriormidline approach including far lateral, and extremelateral routes. However, the transoraltranspharyngeal approach remains the treatment of choice in cases of diseases affecting the craniocervical junction. For very selective cases, the endoscopic endonasal route to this region is another option.We present a case of a ventral FM meningioma treated exclusively with the endoscopic endonasal approach.


Subject(s)
Humans , Female , Adult , Cervical Vertebrae/surgery , Nose Neoplasms/surgery , Natural Orifice Endoscopic Surgery/methods , Foramen Magnum/pathology , Meningioma/surgery , Skull Base Neoplasms/complications , Meningioma/complications
15.
Arq. bras. neurocir ; 37(4): 334-338, 15/12/2018.
Article in English | LILACS | ID: biblio-1362675

ABSTRACT

Foramen magnum meningiomas cause different symptoms based on the size and the location of the tumor. They often present with involvement of the long tracts and of the lower cranial nerves.Ataxia and occipitocervical headache are other common symptoms. In the present study, we report a case of foramen magnum meningioma presenting with cough syncope. A mass lesion located anterolateral to the foramenmagnumwas detected in a 38-year-oldmanduring amagnetic resonance imaging (MRI) exam; the lesion extended from the inferior clivus to the level of the C2 vertebra. The neural axis has pushed towards posterior and contralateral side by the mass. We think that syncope occurred due to the encasement of the vertebral arteries by the tumor in addition to the compression of the neural axis. The posterolateral approach without condylar resection provides a safe surgical plane for total excision of these tumors. In our case, the tumor was totally removed and the syncope episodes were resolved.


Subject(s)
Humans , Male , Adult , Syncope/complications , Cough , Foramen Magnum , Meningioma/surgery , Meningioma/diagnostic imaging , Magnetic Resonance Spectroscopy/methods
16.
Arq. bras. neurocir ; 37(3): 239-241, 2018.
Article in English | LILACS | ID: biblio-1362868

ABSTRACT

Rosai-Dorfman disease is a benign lymphoproliferative disease with rare occurrence in the overall population. The characteristic findings of the disease are emperipolesis on microscopy and S-100 protein positivity on immunohistochemistry. The present report describes the case of a 57-year-old man who presented with repeated seizures, urinary retention, and ataxia. Satisfactory results were obtained with surgical treatment. The diagnosis was confirmed by immunohistochemistry.


Subject(s)
Humans , Male , Middle Aged , Histiocytosis, Sinus/surgery , Meningeal Neoplasms/surgery , Meningioma/surgery , Immunohistochemistry , Histiocytosis, Sinus/diagnosis , Diagnosis, Differential , Meningeal Neoplasms/diagnosis , Meningioma/diagnosis , Microscopy
17.
Rev. otorrinolaringol. cir. cabeza cuello ; 77(4): 431-434, dic. 2017. ilus
Article in Spanish | LILACS | ID: biblio-902799

ABSTRACT

Los meningiomas son los tumores no gliales más comunes del sistema nervioso central constituyendo el 24%-30% de los tumores intracraneales y el 25% de los tumores de médula espinal. Se originan de células de la aracnoides y en general presentan un comportamiento benigno. Existe un subtipo llamado meningioma extracraneal primario o extradural que es poco frecuente y afecta principalmente el área de cabeza y cuello. Debido a su baja prevalencia y síntomas poco característicos son a menudo diagnosticados por fortuna, siendo la inmunohistoquímica fundamental. Se presenta el caso de una mujer adulta con una lesión tumoral en oído medio diagnosticada inicialmente mediante una biopsia incisional como un granuloma de colesterol. Luego del tratamiento quirúrgico y estudio de inmunohistoquímica se concluye el diagnóstico definitivo de meningioma extradural de oído medio. Se analiza la literatura al respecto y se discute sobre su epidemiología, clínica, estudio y manejo.


Meningiomas are the most common non-glial tumors of the central nervous system constituting 24-30% of intracranial tumors and 25% of spinal cord tumors. They originate from arachnoid cells and generally exhibit benign behavior. The subtype primary extracranial meningioma or extradural meningioma that is uncommon and affects the head and neck area. Due to their low prevalence and uncharacteristic symptoms are often diagnosed by fortune, being the immunohistochemistry fundamental. We present the case of an adult woman with a tumor lesion in the middle ear initially diagnosed by an incisional biopsy such as a cholesterol granuloma. After the surgical treatment and immunohistochemical study, the definitive diagnosis of extradural meningioma of the middle ear is concluded. The literature on this subject is analyzed and its epidemiology, clinical practice, study and management are discussed.


Subject(s)
Humans , Female , Middle Aged , Ear Neoplasms/surgery , Ear Neoplasms/diagnosis , Meningioma/surgery , Meningioma/diagnosis , Ear Neoplasms/pathology , Immunohistochemistry , Treatment Outcome , Ear, Middle/pathology , Meningioma/pathology
18.
MedicalExpress (São Paulo, Online) ; 4(4)July-Aug. 2017. tab, graf
Article in English | LILACS | ID: biblio-894357

ABSTRACT

BACKGROUND: Tuberculum sellae meningiomas is a serious challenge for neurosurgeons. It accounts for up to 10% of all intracranial meningiomas. The difficulty in surgically excising a Tuberculum sellae meningioma comes from its anatomical relationship to the optic nerves and chiasm and to the anterior cerebral and internal carotid arteries and their perforators. The authors discuss the main approaches and the complications based on their experience in comparison to previously reported data. METHODS: We report our personal case series of 38 patients with Tuberculum sellae meningiomas; 36 patients under went craniotomy for tumor resection (12 bifrontal, 12 pterional, 6 supraciliary, 4 unilateral frontals, and 2fronto-orbito-zygomatic); in two patients, the excision was performed through an endoscopic endonasal approach. The Simpson grade of meningioma resection as wellhe non-visual morbidity and the mortality rates were analyzed. RESULTS: Thirty-one patients had Simpson grades 1 and 2 excisions, while seven had Simpson grade 4 excisions. The overall rate of non-visual morbidity was 13.15% (5 of 38 patients) and mortality was 5.3% (2 of 38). CONCLUSION: The primary symptom leading to the diagnosis of a Tuberculum sellae meningioma is visual compromise and the main goal of surgeryo achieve improvement of vision. Favorable outcomes were achieved with appropriate selection of surgical approach. More studies are necessary to define the prognostic factors for patients in this scenario.


INTRODUÇÃO: Os meningiomas de tubérculo selar certamente representam um desafio para os neurocirurgiões no que se refere ao manejo cirúrgico. Estes tumores representam até 10% de todos os meningiomas intracranianos. A dificuldade em ressecar cirurgicamente estes meningiomas provém da sua relação com os nervos ópticos, com o quiasma óptico e com as artérias carótidas internas, cerebrais anteriores e suas perfurantes. Discutimos as principais abordagens e as complicações com base em nossa série de pacientes e numa revisão da literatura. CASUÍSTICA E MÉTODOS: Relatamos nossa série de casos pessoais de 38 pacientes com meningiomas de tubérculo selar. Trinta e seis pacientes foram submetidos a craniotomia para ressecção tumoral (12 bifrontal, 12 pterional, 6 supraciliar, 4 unilateral frontal e 2 fronto-orbito-zigomático) e 2 receberam abordagem endoscópica endonasal. A escala de Simpson, bem comoaxas de morbidade e mortalidade foram analisadas durante o período pós-operatório, em função das diferentes abordagens. RESULTADOS: Trinta e um pacientes foram submetidos a excisões de grau I e II da escala de Simpson; os demais foram submetidos a excisão de grau IV da mesma escala. A taxa global de morbidade sem acometimento visual foi de 13,15% (5 de 38 pacientes), enquanto a mortalidade evidenciada foi de 5,3% (2 dentre 38 pacientes). CONCLUSÃO: O principal sintoma que leva ao diagnóstico de meningioma de tubérculo selar é o comprometimento visual, de modo que o principal objetivo da cirurgia é alcançar a melhora da visão nestes pacientes. Os resultados alcançados foram favoráveis quando associados com a seleção apropriada da abordagem cirúrgica. Mais estudos são necessários para definir os fatores prognósticos para os pacientes com meningioma de tubérculo selar após intervenção cirúrgica.


Subject(s)
Humans , Meningeal Neoplasms , Meningioma/surgery , Optic Nerve , Skull Base , Craniotomy/methods
19.
Rev. méd. Hosp. José Carrasco Arteaga ; 9(2): 152-160, Julio 2017. Ilustraciones, Tablas
Article in Spanish | LILACS | ID: biblio-1010079

ABSTRACT

INTRODUCCIÓN: En la actualidad se considera al tratamiento quirúrgico como la primera línea de intervención en meningiomas, el objetivo de esta investigación es describir los resultados y las estrategias actuales en el tratamiento quirúrgico de los meningiomas, que se realizan en el Hospital Santa Inés de Cuenca-Ecuador. METODO: Es un estudio descriptivo sobre el tratamiento quirúrgico de los meningiomas, haciendo énfasis en el tipo de abordaje empleado en el Hospital Santa Inés. Se describen las diferentes localizaciones anatómicas y situaciones fisiológicas específicas de pacientes con meningiomas. RESULTADOS: Se incluyeron 31 pacientes, 11 hombres y 20 mujeres. La edad al momento de la cirugía fue de 13 a 76 años. La localización más frecuente fue la convexidad y parasagital. El 6.45 % de los tumores se reportaron como atípicos. Se logró exéresis Simpson I y II en el 80.6 % de los pacientes. Hubo tres recurrencias, dos de ellas asociadas a la histopatología. No hubo mortalidad operatoria. CONCLUSIONES: La cirugía sigue siendo la primera opción de tratamiento, con resultados mejorados con las técnicas microquirúrgicas actuales y constituye un reto, primero por lograr la exéresis completa del tumor y luego por preservar la función neurológica (au)


BACKGROUD: At present the surgical treatment is considered as the first line in meningiomas, the aim of this study is to describe the outcomes and actual strategies in the surgical treatment of meningiomas treated at the Santa Ines Hospital in Cuenca-Ecuador. METHOD: It is a descriptive study on the surgical treatment of meningiomas, emphasizing the type of approach used in the Hospital Santa Inés. The different anatomical locations and specific physiological situations of patients with meningiomas are described. RESULTS: We included 31 patients, 11 men and 20 women. The age at the time of surgery was the between 13 to 76 years. The most frequent location was convexity and parasagittal. 6.45 % of the tumors were reported as atypical. Simpson I and II excision was achieved in 80.6 % of the patients. There were three recurrences, two associated with histopathology. There was no operative mortality. CONCLUSIONS: The surgery still is the first option of treatment, with better outcome due at the actual microsurgery techniques. The surgery is a challenge, at first achieve complete excision of the tumor and then to preserve the neurological function.(au)


Subject(s)
Humans , Male , Female , Craniotomy , Meningioma/surgery , Recurrence , Brain Neoplasms/classification
20.
Rev. chil. neurocir ; 43(1): 53-58, July 2017. ilus
Article in Spanish | LILACS | ID: biblio-869779

ABSTRACT

A pesar del desarrollo de las técnicas quirúrgicas de base de cráneo, los meningiomas petroclivales constituyen un reto para el neurocirujano debido a su localización y relación con estructuras neurológicas y vasculares críticas. Se reportan 2 pacientes con diagnóstico de meningioma petroclival que recibieron tratamiento por etapas incluyendo derivación ventrículo peritoneal asistida por endoscopia para la hidrocefalia, abordaje endonasal endoscópico (AEE) extendido al ápex petroso, keyhole subtemporal y retromastoideo con remoción de la lesión. La evolución fue satisfactoria. Se concluyó que los abordajes endoscópicos y por etapas constituyen una excelente opción en el tratamiento de los meningiomas petroclivales.


In spite of the development of the skull base surgery techniques, petroclival meningiomas are a challenge for neurosurgeon due to their localization and relationship with neurovascular structures. Those are two patient with diagnostic of petroclival meningioma whom received treatment step by step included ventricle peritoneal shunt with endoscopic guide for hydrocephalus, extended endonasal approach to petrous apex, subtemporal and retrosigmoid keyhole. The endoscopic approach is an excellent option in the treatment of petroclival meningioma.


Subject(s)
Humans , Male , Adult , Middle Aged , Nasal Cavity/surgery , Natural Orifice Endoscopic Surgery/methods , Endoscopy/methods , Petrous Bone/pathology , Meningioma/surgery , Meningioma/diagnostic imaging , Ventriculoperitoneal Shunt , Brain Neoplasms , Skull Base/surgery , Hydrocephalus, Normal Pressure , Hypertension , Magnetic Resonance Imaging/methods , Osteotomy/methods , Paresis , Radiosurgery/methods , Tomography, Spiral Computed/methods
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